| 131. | .drw | Vector graphics (Micrografx Designer, Lotus Freelance, Pro/E) |
| 132. | .ds4 | Vector graphics (Micrografx Designer 4.x) |
| 133. | .dsc | Description file ◊ Discard file (Oracle) ◊ Tag descriptor file (MIME Tag types) |
| 134. | .dsd | Database (DataShaper) ◊ Document structure definition file (Used in XML) |
| 135. | .dsf | Digital Sound File (Delusion) ◊ Document (Micrograpf Designer) |
| 136. | .dsg | Saved game (DOOM) |
| 137. | .dsk | Disk Drivers (Novell NetWare) ◊ Project desktop (Borland C++, Turbo Pascal) |
| 138. | .dsl | DSSSL Style Sheet |
| 139. | .dsm | Dynamic Studio music module (MOD) ◊ Macro (Microsoft Developer Studio) ◊ Music (Digital Sound Module) (DSI) ◊ Music module file (DSIK) |
| 140. | .dsn | Design (Object System Designer) ◊ ODBC data source ◊ Schematic file (Orcad Schematic Capture) |
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