| 1. | .$$s | Spreadsheet (OS/2) |
| 2. | .s | Assembly language source code file.s (Unix) ◊ Foreign assembly source file (Modula-3) ◊ Macro source file (MultiEdit) ◊ Scheme language source code file |
| 3. | .s$$ | Temporary sort file (Sprint) |
| 4. | .s1k | S1000 Simnet Format |
| 5. | .s3i | Sample file (Digiplayer - ST3) |
| 6. | .s3m | Music (16 channels) (Scream Tracker III) |
| 7. | .saf | Spatial Archive Interchange Format |
| 8. | .sai | Encrypted video file (Integrated Sensors) |
| 9. | .saif | Spatial Archive Interchange Format |
| 10. | .sal | Datafile (SORITEC) |