| 71. | .sds | MIDI Sample DUMP Standard File |
| 72. | .sdt | Template (SmartDraw) |
| 73. | .sdts | Spatial Data Transfer Standard |
| 74. | .sdv | Semicolon Divided Values file |
| 75. | .sdw | Datafile (Scenery data for Windows) ◊ Sound (Raw Signed DWord (32bit) data) ◊ Vector graphics (Ami Draw) |
| 76. | .sdx | Sample DUMP Exchange File |
| 77. | .sea | Self-extracting compressed Macintosh file archive (Compact Pro) ◊ SoundBlaster effect preset for your sound card |
| 78. | .sec | Diskreet encrypted file (Diskreet) ◊ Secret key ring file (Pretty Good Privacy) ◊ Secured animation file (Disney Animation Studio) |
| 79. | .sed | Screen editor script files (SED) |
| 80. | .sel | Data file (Copy Books) |
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