| 11. | .sam | Sound (Signed 8bit Sample data) ◊ Text document (Ami Word Processor) |
| 12. | .sar | Compressed file archive (SAR) |
| 13. | .sas | SAS source code file (VMS) |
| 14. | .sat | Vector graphics (ACIS 2D/3D) |
| 15. | .sav | Saved backup or configuration data ◊ Saved game situation (eg. NetHack) |
| 16. | .sb | Sound (Raw Signed PCM Byte (8bit) data) |
| 17. | .sb! | Locking file (Superbase) |
| 18. | .sbd | Data definition file (Superbase) ◊ Data file (Storyboard Editor) |
| 19. | .sbf | File data (Superbase) |
| 20. | .sbi | Bitmap graphics (Santa Barbara Instruments Astronomical Image) ◊ Sound Blaster Instrument (Creative Labs) |
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