| 101. | .ipx | IPIX file (IPIX) |
| 102. | .iqy | Internet inquiry (Microsoft Excel) |
| 103. | .irc | Sound (IRCAM format) |
| 104. | .iris | Bitmap graphics (Irix RGB image format) |
| 105. | .irs | Resource (WordPerfect) |
| 106. | .irtp | Graphics (Graphicon-2000 Interactive Real-Time PHIGS) |
| 107. | .is | Intermediate assembly file (Modula-3) |
| 108. | .isd | Spelling Checker dictionary (RapidFile) |
| 109. | .ish | Compressed file archive (ISH) |
| 110. | .iso | Bitmap graphics (CALS ISO 8613) ◊ CD Image File (ISO 9660 CD-ROM file system standard) ◊ ISO-9660 table (International Standards Organization) |
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