| 181. | .so | Dynamic Shared Object (Unix library) |
| 182. | .sol | MATRA prelude solids ◊ Solution eg. game walkthroughs |
| 183. | .som | Network serial numbers (Quattro Pro) ◊ Sort information (Paradox) |
| 184. | .son | Song file (Creative Labs SoundBlaster Studio II) |
| 185. | .sou | Sound file (Creative Labs SoundBlaster Studio) |
| 186. | .sox | Schema for object oriented XML |
| 187. | .sp | Compressed file archive (Splint) ◊ Data (Spice) |
| 188. | .sp4 | Saved game (Roller Coaster Tycoon) |
| 189. | .spc | Bitmap graphics (Atari compressed Spectrum file) ◊ Program (Microsoft Multiplan) ◊ SNES Audio (music) ◊ SPC format for spectral and chromatographic data ◊ Temporary file (WordP… 0.3 KB |
| 190. | .spd | Scalable font (Speedo) (Harvard Graphics 3.0) ◊ Sound (Speach Data file) |